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“Phosphosignaling and membrane-associated proteins that influence drought response and plant growth.”

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Thursday 04 July 2019, 11:00 - 12:30


The Verslues laboratory is interested in the molecular mechanisms of how plants can acclimate and maintain growth during moderate severity drought stress. We particularly focus on phospho-signaling and plasma membrane-associated mechanisms impacting drought response. Phosphoproteomics of Highly ABA-Induced 1 (HAI1) and Clade E Growth Regulating (EGR) protein phosphatases identified nuclear and cytoskeleton/plasma membrane-associated proteins, respectively.  The HAI1 target proteins AHL10 and HIN1 are regulators of stress-induced gene expression and alternative splicing.  EGRs and their target protein MASP1 are potent regulators of cell division activity during drought stress.  Plasma membrane associated proteins that affect drought resistance, such as the EGR phosphatases, are of particular interest because many ideas of the poorly understood sensing and early signaling mechanisms plants use to detect changes in water status focus on events at the cell wall-plasma membrane-cytoskeleton interface.  Our laboratory also continues to investigate other plasma membrane-associated proteins involved in drought response including At14a-Like 1 (AFL1) which accumulates to high levels during drought and affects endocytosis (FM4-64 uptake) and actin filament organization.  How AFL1 affects these process as well as how stress and AFL1 control the plasma membrane proteome are under investigation.

Location Jozef Schell Seminar Room
Contact Prof Paul Verslues
Institute of Plant and Microbial Biology
Academia Sinica